Canine Parvovirus Monoclonal Antibody

What is canine parvovirus monoclonal antibody?

Canine parvovirus monoclonal antibody (also known as parvovirus mAb) is an antibody injection used to treat parvovirus in dogs that are 8 weeks of age and older.

This medication is conditionally approved by the Food and Drug Administration (FDA) in the United States. It is not currently available in Canada. Any off label (extra label) use is strictly prohibited.

How do I give my pet canine parvovirus monoclonal antibody?

• Canine parvovirus monoclonal antibody comes in an injectable form given by your veterinarian as a single injection.
• Injections are given intravenously (into the vein).
• Dispose of used sharps in a designated sharps container.

This medication should start working immediately after the injection.

What if I miss giving my pet the medication?

This medication is given as a single-dose injection by your veterinarian.

Are there any potential side effects from canine parvovirus monoclonal antibody?

Canine parvovirus monoclonal antibody may cause the following side effects:

• Redness, mild pain or swelling at injection site
• Diarrhea

Serious adverse reactions may occur. If any of the following signs develop, stop giving canine parvovirus monoclonal antibody and contact your veterinarian immediately:

• An allergic reaction such as irregular breathing, rash, fever, puffiness and swelling around the face

Drug sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses, but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment. 

Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. The effects of this medication are expected to last 4–6 weeks.

Are there any risk factors for this medication?

DO NOT USE canine parvovirus monoclonal antibody in:

• Dogs less than 8 weeks of age
• Any species other than dogs

USE WITH CAUTION in:

• Pregnant dogs

Are there any drug interactions I should be aware of?

The following medications should be used with caution when given with canine parvovirus monoclonal antibody:

• Parvovirus vaccines

Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Is any monitoring needed with this medication?

• Follow your veterinarian’s directions for lab work monitoring during treatment.
• At home, monitor for any abnormal changes. If any occur, discontinue the medication and contact your veterinarian.

How do I store canine parvovirus monoclonal antibody?

• Your veterinarian will store the medication at a temperature of less than -15°C (-5°F), in a freezer.
• Use medication immediately after thawing and discard unused product.
• Keep medication out of reach of children and pets.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet's weight and symptoms.