Chlorhexadine Acetate Dental

What is chlorhexadine acetate dental? 

Chlorhexadine acetate dental (Nolvadent®) is an oral health rinse for dogs and cats. It is used to improve periodontal (oral) health by promoting healthy gums and teeth. Nolvadent assists in the maintenance of a healthy and pleasant-smelling mouth in dogs and cats by removing food particles and other debris from the teeth and gum line.

The U.S. Food and Drug Administration (FDA) does not review non-drug health supplements (e.g., herbals, nutraceuticals, shampoos, and other supplements) for safety or effectiveness before they are sold to the public. 

Manufacturers of non-drug health supplements must ensure their supplements are safe and labeled accurately. The FDA requires that these non-pharmaceuticals contain a disclaimer that says, “This supplement is not intended to diagnose, treat, cure or prevent any disease.” 

Health Canada licenses “veterinary health supplements” after reviewing safety, efficacy, and manufacturing information provided by the manufacturer. These supplements are not tested by Health Canada.

Your veterinarian is the best source of information about the safety of non-drug health supplements in pets. Just because a supplement is natural does not mean it is safe. All medicines and medicinal plants are potentially toxic if used inappropriately or given at high doses. Supplements can also have side effects, like pharmaceuticals. Few supplements and herbs have been subjected to rigorous scientific trials to determine their efficacy. 

Although the information in this handout may be helpful, it may also be incomplete and may not represent the full range of effects the supplement could have on your pet.

How do I give my pet chlorhexadine acetate dental?

• Chlorhexadine acetate dental is given orally (by mouth), either by rinsing the teeth and gums, or by applying with a toothbrush. 
• Be careful not to touch the gum with the nozzle, as it can easily injure the gums.
• Give this supplement on a full or empty stomach.
• Ideally, give this supplement at the same time daily.
• Use of chlorhexadine acetate dental should not be considered a substitute for sound veterinary dental treatment. This product should be used under the direction of a veterinarian who can advise on a complete oral health program.

This product should take effect within 2–4 weeks, and improvement in clinical signs should follow. 

What if I miss giving my pet chlorhexadine acetate dental?

If you miss an application, give it as soon as you remember. However, if it is almost time for the next scheduled application, skip the missed dose and resume the regular schedule. Do not give the pet two doses at once.

Are there any potential side effects from chlorhexadine acetate dental?

Chlorhexadine acetate dental may cause the following side effects:

• Staining of tooth surfaces (with prolonged use; avoid by applying with a toothbrush)

Sensitivities can develop over time, with repeated exposure. Your pet may have no reaction after the first few doses but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment. 

Other side effects may occur. If you notice anything unusual, discontinue use and contact your veterinarian immediately. This supplement should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease.

Are there any risk factors for this supplement?

DO NOT USE chlorhexadine acetate dental in:

• Pets that are allergic to it.

Are there any drug interactions I should be aware of?

There are no documented drug interactions for this medication. Make sure your veterinarian is aware of any medications (including vitamins, supplements or herbal therapies) that your pet is taking before starting any new treatment.

Is any monitoring needed with this supplement?

• Follow your veterinarian’s recommendations regarding when your pet needs to be rechecked and what tests may need to be performed before and during treatment with this product. 
• If your pet is being treated at home, monitor it closely for any changes including improvements or side effects such as those noted above. Contact your veterinarian with any changes.

How do I store chlorhexadine acetate dental?

• Store at room temperature (59°F-86°F or 15°C-30°C).
• Ensure bottles are tightly sealed and secured inside a cabinet to prevent accidental ingestion. 
• Store in a cool dry place away from sunlight. 
• Keep out of reach of children.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the supplement, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet’s weight and symptoms. Adverse effects should also be reported to the FDA or Health Canada,