Acyclovir Ophthalmic

What is acyclovir ophthalmic?

Acyclovir ophthalmic is a topical antiviral used in cats to treat herpes infections in the eyes.

It is used off label (extra label) in veterinary medicine. Many drugs are commonly prescribed for off-label use in veterinary medicine. 

“Off label” means the drug is being used in a way that has not been reviewed or approved by the U.S. Food and Drug Administration (FDA) or Health Canada. In these instances, follow your veterinarian’s directions and cautions very carefully, as their directions may be significantly different from those on the label.

How do I give my pet acyclovir ophthalmic?

• Acyclovir ophthalmic comes in an ointment form. It is specially compounded.
• Give ointment topically, directly into the eye.
• Wash your hands before giving your pet this medication.
• Do not allow the dropper tip to touch your animal’s eye or any other surface to prevent contamination.
• If you are administering more than one eye medication to your pet, wait 5 to 10 minutes between each medication. Give eye drops before eye ointments.
• Give this medication to your pet for the entire time prescribed by your veterinarian, even if it appears that your pet is feeling better.

This medication will take effect in 1–2 hours, though you may not see effects outwardly.

What if I miss giving my pet the medication?

If you miss a dose, give it as soon as you remember, and then continue with the regular dosing schedule. However, if it is almost time for the next dose, skip the missed dose and resume the regular dosing schedule. Do not give the pet two doses at once.

Are there any potential side effects?

Acyclovir ophthalmic may cause the following side effects:

• Mild pain, irritation, or redness in or around the eye
• Nausea or vomiting
• Dizziness or sleepiness

Serious adverse reactions may occur. If any of the following signs develop, stop giving acyclovir ophthalmic and contact your veterinarian immediately:

• An allergic reaction such as irregular breathing, rash, fever, puffiness and swelling around the face
• Signs of kidney problems (e.g., changes in appetite, changes in urination, lethargy)
• Unusual bruising or bleeding

Drug sensitivities can develop over time with repeated exposure. Your pet may have no reaction after the first few doses, but may develop a sensitivity later. It is important to watch for signs of an allergic reaction over the entire course of treatment.

Other side effects may occur. If you notice anything unusual, contact your veterinarian immediately. This short-acting medication should stop working within 24 hours.

Are there any risk factors for this medication?

DO NOT USE acyclovir ophthalmic in cats that:

• Are allergic to any component
• Will swallow the medication

USE WITH CAUTION in cats that:

• Are pregnant or nursing

Are there any drug interactions I should be aware of?

There are no documented drug interactions for acyclovir ophthalmic. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking before starting any new treatment.

Is any monitoring needed with this medication?

• Your veterinarian may schedule a follow-up visit after the course of medication is complete to ensure the condition has been cleared and/or do additional testing to ensure this is the right medication for the type of condition present. In this case, follow your veterinarian’s directions.
• At home, monitor for any abnormal changes. If any occur, discontinue the medication and contact your veterinarian.

How do I store acyclovir ophthalmic?

• Store in a tightly sealed container, at room temperature, protected from light
• Store compounded forms of this medication according to the label.
• Keep medication out of reach of children and pets.

What should I do in case of emergency?

If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. If they are not available, follow their directions in contacting an emergency facility. Be prepared to provide information about the product and your pet’s weight and symptoms.